Infection and inflammation, innate and adaptive immune response, cells that are involved in the different pathways and what the XN-Series analysers have to do with all this are the topics covered within this article.
Malaria has plagued humankind since ancient times and is still a significant threat to around half of the world’s population. Although malaria infections are primarily a problem in tropical regions, they occur ever more frequently also in non-endemic areas due to tourism and globalisation.
During HSCT patients suffer from many critical conditions such as thrombocytopenia or infections, as well as it is necessary to closely monitor the engraftment. This white paper explains how a Sysmex haematology analyser can answer your clinical demands.
A deeper insight about an activation of the immune response of patients can be acquired from newly available diagnostic parameters that support differentiation between inflammation and infection, different pathogenic causes of infection (viral versus bacterial) and different types of immune response: early innate, cellular or humoral immune response.
Platelets are normally measured by impedance, but when interferences are present, this may lead to a wrong count. There are alternatives methods for platelet measurement that are here explained in detailed, like the fluorescence flow cytometry and the accurate count provided by the PLT-F channel.
In patients treated with haemodialysis (HD), the interaction with the dialysis membrane can disturb haemostatic balance. Interaction of platelets with the membrane can lead to platelet activation and adhesion, which both affects membrane performance and the viability of platelets. By looking at platelet characteristics and morphology, as well as markers of platelet activation, this process can be characterized in more detail.
Every step in the process of phlebotomy affects the quality of the specimen and is thus important for preventing laboratory error and patient injury. This document provides guidance on blood sampling and reiterates the accepted principles for drawing and collecting blood.